BDBM50454922 CHEMBL4205607

SMILES CNC(=O)c1c(oc2cc3N(Cc4cnnn4[C@H](C)c3cc12)S(C)(=O)=O)-c1ccc(F)cc1

InChI Key InChIKey=AKXKWVKQWVIUCK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454922   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Presidio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50454922(CHEMBL4205607)
Affinity DataEC50:  38nMAssay Description:Inhibition of HCV genotype 1b NS5B polymerase infected in human HuH7 replicon cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Presidio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50454922(CHEMBL4205607)
Affinity DataEC50:  617nMAssay Description:Inhibition of HCV genotype 1a NS5A polymerase infected in human HuH7 replicon cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed