BDBM50454887 CHEMBL4204771

SMILES CNC(=O)c1c(oc2cc3N(CCCCc3cc12)S(=O)(=O)C1CC1)-c1ccc(F)cc1

InChI Key InChIKey=ZMACZJBZKBQMNE-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50454887   

TargetNonstructural protein 5A(Hepacivirus C)
Presidio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50454887(CHEMBL4204771)
Affinity DataEC50:  423nMAssay Description:Inhibition of HCV genotype 1a NS5A polymerase L31V/Y93H double mutant infected in human HuH7 replicon cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Presidio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50454887(CHEMBL4204771)
Affinity DataEC50:  335nMAssay Description:Inhibition of HCV genotype 1a NS5A polymerase infected in human HuH7 replicon cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Presidio Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50454887(CHEMBL4204771)
Affinity DataEC50:  73nMAssay Description:Inhibition of HCV genotype 1b NS5B polymerase infected in human HuH7 replicon cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed