BDBM50454716 CHEMBL4215048

SMILES CNC(=O)c1ccnc(OCCCCN2CCN(CC2)c2nsc3cc(F)ccc23)c1

InChI Key InChIKey=IPVLSOVWVUCPMD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50454716   

Target5-hydroxytryptamine receptor 2A(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50454716(CHEMBL4215048)
Affinity DataIC50: 52nMAssay Description:Antagonistic activity at human 5-HT2A receptor assessed as calcium flux after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50454716(CHEMBL4215048)
Affinity DataIC50: 89nMAssay Description:Antagonistic activity at human dopamine D2 receptor measured after 60 mins by Lance Ultra cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50454716(CHEMBL4215048)
Affinity DataEC50:  176nMAssay Description:Agonistic activity at human 5-HT1A receptor measured after 60 mins by Ultra Lance cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed