BDBM50454410 CHEMBL4212641

SMILES COc1cccc(F)c1-c1ccnc(Nc2cccc(Cn3cnc4ccccc34)c2)n1

InChI Key InChIKey=MDOPSPOMDXUNGM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454410   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50454410(CHEMBL4212641)
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal GST-HIS6 fusion protein tagged human full length CDK9 (M1 to F372 residues)/N-terminal GST-HIS6 fusion protein tagged human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50454410(CHEMBL4212641)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of human PLK1 kinase domain using 5-TAMRA-RGSFNDTLDFD-NH2 substrate and ATP incubated for 90 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed