BDBM50454190 CHEMBL4202767

SMILES CCOc1c(Cl)cc(cc1OC(C)C)C(=O)Nc1ccc(C(O)=O)c(C)c1

InChI Key InChIKey=ZWBXDTPGJLLDCM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50454190   

TargetCytochrome P450 2C19(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50454190(CHEMBL4202767)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50454190(CHEMBL4202767)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50454190(CHEMBL4202767)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50454190(CHEMBL4202767)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50454190(CHEMBL4202767)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-9-cis-retinoic acid from recombinant human full length RXRbeta after 24 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50454190(CHEMBL4202767)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-9-cis-retinoic acid from recombinant human full length RXRalpha after 16 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
King'S College

Curated by ChEMBL
LigandPNGBDBM50454190(CHEMBL4202767)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed