BDBM50454137 CHEMBL1321988

SMILES S=C=Nc1cccc(NC(=S)NCCCCNC(=S)Nc2cccc(c2)N=C=S)c1

InChI Key InChIKey=QOHNRGHTJPFMSL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50454137   

TargetP2Y purinoceptor 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50454137(CHEMBL1321988)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at P2Y6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50454137(CHEMBL1321988)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced inositol-1-phosphate accumulation pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50454137(CHEMBL1321988)
Affinity DataIC50: 98nMAssay Description:Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced inositol-1-phosphate accumulation prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50454137(CHEMBL1321988)
Affinity DataIC50: 3.95E+4nMAssay Description:Antagonist activity at human P2Y6R expressed in HEK293 cells assessed as inhibition of UDP-induced IP3 production preincubated for 0.5 hrs followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetP2Y purinoceptor 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50454137(CHEMBL1321988)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human P2Y6R expressed in human 1321N1 cells assessed as inhibition of UDP-induced calcium mobilization incubated for 5 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetP2Y purinoceptor 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50454137(CHEMBL1321988)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human P2Y6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed