BDBM50453744 CHEMBL4205402

SMILES C1CNCc2ccc3ccc(CNCCNCCNCc4ccc5ccc(CNCCN1)cc5c4)cc3c2

InChI Key InChIKey=GOBPKVITNWSXKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50453744   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50453744(CHEMBL4205402)
Affinity DataIC50: 57nMAssay Description:Inhibition of human APE1 assessed as reduction in abasic sites DNA cleavage using 6-FAM/TAMRA labelled 17-Tphi as substrate by fluorescence-based ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed