BDBM50453191 CHEMBL4214231

SMILES OCCCCNc1nc(Nc2ccc(CN3CCOCC3)cc2)c2ncn(C3CCCC3)c2n1

InChI Key InChIKey=CHJNEMUDJJDONV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50453191   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50453191(CHEMBL4214231)
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant human FLT3 (R571 to S993 residues) ITD mutant expressed in Sf9 insect cells using poly (Ala,Glu,L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50453191(CHEMBL4214231)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of recombinant human 3C cleavage site/N-terminal GST-His6 fused PDGFR alpha C-terminal fragment (Q551 to L1089 residues) harboring V561D m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed