BDBM50453141 CHEMBL4217325

SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1)N1CCN(CCOCCOCCNC(=O)CNc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)CC1

InChI Key InChIKey=WXNUIPVZMJMPNM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50453141   

TargetALK tyrosine kinase receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453141(CHEMBL4217325)
Affinity DataIC50: 180nMAssay Description:Induction of ALK degradation in human KARPAS299 cells after 16 hrs by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453141(CHEMBL4217325)
Affinity DataIC50: 50nMAssay Description:Induction of ALK degradation in human Kelly cells after 16 hrs by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453141(CHEMBL4217325)
Affinity DataIC50: 10nMAssay Description:Induction of ALK degradation in human NCI-H3122 cells after 16 hrs by immunoblot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed