BDBM50453132 CHEMBL4207725

SMILES CC1(C)NC(=O)C[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O)C(N)=O

InChI Key InChIKey=CJCOTNMGGCNQIS-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50453132   

TargetMelanocortin receptor 4(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453132(CHEMBL4207725)
Affinity DataEC50:  6.70nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453132(CHEMBL4207725)
Affinity DataEC50:  87nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453132(CHEMBL4207725)
Affinity DataIC50: 601nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453132(CHEMBL4207725)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453132(CHEMBL4207725)
Affinity DataEC50:  76nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453132(CHEMBL4207725)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453132(CHEMBL4207725)
Affinity DataIC50: 5.20nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453132(CHEMBL4207725)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed