BDBM50453031 CHEMBL4211143

SMILES CC(C)n1cc(NC(=O)c2ccc(Nc3ccc4ccccc4c3)cc2C)c(=O)n(CC(=O)N[C@H]2CC(=O)OC2O)c1=O

InChI Key InChIKey=PFAHWTBDHYAREP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50453031   

TargetCaspase-1(Human)
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453031(CHEMBL4211143)
Affinity DataIC50: 66nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed