BDBM50452871 CHEMBL4218256

SMILES N[C@H]1CCN(C1)c1cc2n(C3CC3)c(=O)c3ncnn3c2cc1F

InChI Key InChIKey=RHHCTNLLLQCYIV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50452871   

TargetCytochrome P450 3A4(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated midazolam metabolism in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG transfected in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated testosterone metabolism in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed