BDBM50452870 CHEMBL4203118

SMILES Fc1cc2c(cc1-c1ccncc1)n(C1CC1)c(=O)c1nccn21

InChI Key InChIKey=UZAPAHIWOLYIFO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50452870   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP3A4-mediated midazolam metabolism in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP3A4-mediated testosterone metabolism in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG transfected in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed