BDBM50452778 CHEMBL4218253

SMILES Cn1ccc(n1)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(CC2=C(CCC(C)(C)C2)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=MZRBZVXBTQWGTK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452778   

TargetApoptosis regulator Bcl-2(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50452778(CHEMBL4218253)
Affinity DataIC50: 67nMAssay Description:Displacement of Bax-derived peptide from Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50452778(CHEMBL4218253)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of Bad-derived peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed