BDBM50452661 CHEMBL4213137

SMILES NC(=O)c1ccc(OCc2ccc(F)cc2)cc1

InChI Key InChIKey=KYFVQTLQFWOEDC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50452661   

TargetAmine oxidase [flavin-containing] B(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50452661(CHEMBL4213137)
Affinity DataIC50: 271nMAssay Description:Inhibition of recombinant human MAO-B using benzylamine as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50452661(CHEMBL4213137)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50452661(CHEMBL4213137)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50452661(CHEMBL4213137)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed