BDBM50452616 CHEMBL4218681

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(NS(=O)(=O)c3ccc(I)cc3)cc21)C(O)=O

InChI Key InChIKey=BENVRUSKAIOVEH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452616   

TargetCollagenase 3(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452616(CHEMBL4218681)
Affinity DataIC50: 403nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452616(CHEMBL4218681)
Affinity DataIC50: 297nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed