BDBM50452335 CHEMBL2113484

SMILES c1ccc(cc1)CCCNc2c3c(ncn2)n(cn3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O

InChI Key InChIKey=UBRRRMDHTZACMR-UHFFFAOYSA-N

Data  7 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50452335   

TargetAdenosine receptor A2a(Human)
Institute of Medical Biology Pas

Curated by ChEMBL
LigandPNGBDBM50452335(CHEMBL2113484)
Affinity DataIC50: 2.03E+4nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HeLa cells by beta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50452335(CHEMBL2113484)
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]PIA binding to rat cortical adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50452335(CHEMBL2113484)
Affinity DataKi:  23nMAssay Description:Binding affinity to adenosine A1 receptor in rat whole brain membranes by [3H]N6-cyclohexyladenosine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Institute of Medical Biology Pas

Curated by ChEMBL
LigandPNGBDBM50452335(CHEMBL2113484)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in HeLa cell membrane incubated for 180 mins by microplate beta scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Institute of Medical Biology Pas

Curated by ChEMBL
LigandPNGBDBM50452335(CHEMBL2113484)
Affinity DataKi:  79nMAssay Description:Displacement [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membrane incubated for 60 mins by microplate beta scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Parke-Davis Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50452335(CHEMBL2113484)
Affinity DataKi:  420nMAssay Description:Binding affinity to A2 adenosine receptor in rat striatal membranes by [3H]NECA (1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuranuronamide)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Parke-Davis Pharmaceutical Research Division

Curated by ChEMBL
LigandPNGBDBM50452335(CHEMBL2113484)
Affinity DataKi:  455nMAssay Description:Affinity for adenosine A2 receptor at rat striatal membrane using 5 nM [3H]CGS-21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Institute of Medical Biology Pas

Curated by ChEMBL
LigandPNGBDBM50452335(CHEMBL2113484)
Affinity DataKi:  2.05E+3nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HeLa cell membrane incubated for 30 mins by microplate beta scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed