BDBM504523 US11040966, Example 2.1::[(2S,4S)-2-(5-Chloro-4-methyl-1H-benzoimidazol-2-yl)-4-fluoro-pyrrolidin-1-yl]-(5-methyl-2-[1,2,3]triazol-2-yl-phenyl)-methanone

SMILES Cc1ccc(c(c1)C(=O)N1C[C@@H](F)C[C@H]1c1nc2c(C)c(Cl)ccc2[nH]1)-n1nccn1

InChI Key InChIKey=BHKUHYOMYDNXGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504523   

TargetOrexin/Hypocretin receptor type 1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM504523([(2S,4S)-2-(5-Chloro-4-methyl-1H-benzoimidazol-2-y...)
Affinity DataIC50: 56nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM504523([(2S,4S)-2-(5-Chloro-4-methyl-1H-benzoimidazol-2-y...)
Affinity DataIC50: 53nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent