BDBM50452052 CHEMBL4210217

SMILES Cc1cc2c(o1)c(cc1nc(Nc3c(Cl)cncc3Cl)[nH]c21)C(=O)NC1CCCCC1

InChI Key InChIKey=FTBDXILHVULBCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452052   

TargetProstaglandin E synthase(Human)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50452052(CHEMBL4210217)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50452052(CHEMBL4210217)
Affinity DataIC50: 39nMAssay Description:Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta induced PGE2 production pretreated for 30 mins followed by IL-1beta additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed