BDBM50452028 CHEMBL4214128

SMILES Nc1cc2nsnc2cc1C#C

InChI Key InChIKey=BLLBUUTUIRJMFA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50452028   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50452028(CHEMBL4214128)
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of GST-tagged PTP1B (unknown origin) using pNPP as substrate measured for 3 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50452028(CHEMBL4214128)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of SHP1 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50452028(CHEMBL4214128)
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of SHP2 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed