BDBM50451895 CHEMBL4216874

SMILES CC1C(CN1C(=O)c1sc2nnc(C)c(C)c2c1N)c1cccc(F)c1

InChI Key InChIKey=VVSZXIDQYRKLBW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451895   

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50451895(CHEMBL4216874)
Affinity DataEC50:  1.46E+3nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50451895(CHEMBL4216874)
Affinity DataEC50:  1.45E+3nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed