BDBM50451725 CHEMBL4203828

SMILES Cn1cc2CC(C)(C)CCc2c1C(=O)NCc1cccnc1OCC(F)(F)F

InChI Key InChIKey=RSCITLWVXGSAHD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451725   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451725(CHEMBL4203828)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant human Cav3.2 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451725(CHEMBL4203828)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of recombinant human Cav3.3 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451725(CHEMBL4203828)
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant human Cav3.1 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed