BDBM50451622 CHEMBL4218185

SMILES O=CCNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=HGCGAOORAMFLTO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451622   

TargetCysteine protease ATG4B(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50451622(CHEMBL4218185)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCysteine protease ATG4B(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50451622(CHEMBL4218185)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50451622(CHEMBL4218185)
Affinity DataKi:  7.90nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-phe-Arg-7-amido-4-methylcoumarin as substrate by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed