BDBM50450965 CHEMBL4204865

SMILES Cn1cc(NC(=O)c2cc(NC(=O)Nc3cc(cc(c3)C(F)(F)F)C(=O)Nc3cc(C(=O)Nc4ccc5c(cccc5c4S([O-])(=O)=O)S([O-])(=O)=O)n(C)c3)cc(c2)C(F)(F)F)cc1C(=O)Nc1ccc2c(cccc2c1S([O-])(=O)=O)S([O-])(=O)=O

InChI Key InChIKey=SYTKVQIXVBXRQG-UHFFFAOYSA-J

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50450965   

TargetHeparanase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50450965(CHEMBL4204865)
Affinity DataIC50: 660nMAssay Description:Inhibition of heparanase (unknown origin) assessed as reduction in AGA*IA cleavage after 3 hrs by WST1 dye based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed