BDBM50450899 CHEMBL4214962

SMILES [H]/N=C(\CF)/NCCC[C@@H](c1nc2c(n1C)cccc2OC)NC(=O)c3cccc4c3C(=O)NC4

InChI Key InChIKey=DMTSALXYYYZIBF-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50450899   

TargetProtein-arginine deiminase type-2(Human)
University of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50450899(CHEMBL4214962)
Affinity DataEC50:  400nMAssay Description:Binding affinity to human PAD2 expressed in HEK293T cells assessed as decrease in histone H3 citrulination incubated for 3 hrs in presence of ionomyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-2(Human)
University of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50450899(CHEMBL4214962)
Affinity DataEC50:  9.50E+3nMAssay Description:Binding affinity to human PAD2 expressed in HEK293T cells assessed as protein occupancy preincubated for 15 mins followed by ionomycin addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed