BDBM50450826 CHEMBL4214270

SMILES Oc1cc(Cl)ccc1NC(=S)Nc1ccc2[nH]ccc2c1

InChI Key InChIKey=SFSZUMBFIBZUDZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50450826   

TargetAmine oxidase [flavin-containing] A(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50450826(CHEMBL4214270)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human purified MAO-A expressed in insect cell membranes assessed as reduction in conversion of kynuramine to 4-hydroxyquinoline by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50450826(CHEMBL4214270)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human membrane bound MAO-A expressed in insect cell membranes assessed as reduction in conversion of kynuramine to 4-hydroxyquinoline b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50450826(CHEMBL4214270)
Affinity DataIC50: 300nMAssay Description:Inhibition of human membrane bound MAO-B expressed in insect cell membranes assessed as reduction in conversion of kynuramine to 4-hydroxyquinoline b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50450826(CHEMBL4214270)
Affinity DataIC50: 638nMAssay Description:Inhibition of recombinant human MAO-B using kynuramine as substrate incubated for 20 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed