BDBM50450537 CHEMBL146206

SMILES [H][C@](CCC(O)=O)(NC(=O)Nc1ccccc1)C(=O)N(CC(=O)N(C(C)C)c1ccccc1)c1ccccc1

InChI Key InChIKey=UYHYPASNCCHSSE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50450537   

TargetGastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450537(CHEMBL146206)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecystok...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450537(CHEMBL146206)
Affinity DataIC50: 1.59E+3nMAssay Description:Tested for the 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50450537(CHEMBL146206)
Affinity DataEC50:  210nMAssay Description:Concentration of compound that induced 50% of the maximal contraction in guinea pig gallbladder tissue when tested in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article