BDBM50450503 CHEMBL3218118

SMILES OC1(COc2ccc(C#N)c(F)c2)CN(C1)S(=O)(=O)c1ccc(Cl)cc1Cl

InChI Key InChIKey=RZAIRBXIVAVGHE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50450503   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
TBA

Curated by ChEMBL

LigandBDBM50450503(CHEMBL3218118)Copy SMILESCopy InChI

Affinity DataIC50: 50nMAssay Description:Antagonist activity at human TRPV4 expressed in BHK/AC9 or HEK MSR2 cells assessed as inhibition of PF-04674114-induced Ca2+ flux pre-incubated for 1...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
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TargetTransient receptor potential cation channel subfamily V member 4(Human)
TBA

Curated by ChEMBL

LigandBDBM50450503(CHEMBL3218118)Copy SMILESCopy InChI

Affinity DataIC50: 4nMAssay Description:Antagonist activity at TRPV4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
8/14/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL