BDBM50450081 CHEMBL4159820

SMILES COc1ccc(cc1)-c1nc(CNC(=O)\C=C\c2ccc(Cl)cc2)cc2c3ccccc3[nH]c12

InChI Key InChIKey=BPTZIKGWGZUMMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50450081   

TargetTopoisomerase I(Bovine)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50450081(CHEMBL4159820)
Affinity DataIC50: 14nMAssay Description:Inhibition of calf thymus topoisomerase 1-mediated relaxation of supercoiled pBR322 DNA measured after 30 mins by agarose gel electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed