BDBM50449975 CHEMBL4164334

SMILES CC(C)[C@H](N)C(=O)Nc1nc(C)c(s1)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(C)cc2)c1

InChI Key InChIKey=VKOFOXNLTIKFHE-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50449975   

TargetPhosphatidylinositol 4-kinase alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50449975(CHEMBL4164334)
Affinity DataIC50: 164nMAssay Description:Inhibition of PI4K3A (unknown origin) using PI:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50449975(CHEMBL4164334)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50449975(CHEMBL4164334)
Affinity DataIC50: 194nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50449975(CHEMBL4164334)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human PIK3C2A catalytic domain expressed in Baculovirus expression system using PI as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50449975(CHEMBL4164334)
Affinity DataIC50: 248nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human PIK3C2B catalytic domain expressed in Baculovirus expression system using PI as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50449975(CHEMBL4164334)
Affinity DataIC50: 405nMAssay Description:Inhibition of GST-tagged full length recombinant human VPS34 expressed in Baculovirus expression system using PI:PS as substrate preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50449975(CHEMBL4164334)
Affinity DataIC50: 68nMAssay Description:Inhibition of PI4K3B (unknown origin) using PI:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50449975(CHEMBL4164334)
Affinity DataIC50: 156nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50449975(CHEMBL4164334)
Affinity DataIC50: 23nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed