BDBM50449908 CHEMBL4168217

SMILES CCOc1cc(ccc1C1=N[C@@H]([C@@H](N1C(=O)N1CCN(CCCCCCC(=O)NO)CC1)c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(C)(C)C

InChI Key InChIKey=ODMAGXZOJNLPBL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449908   

TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50449908(CHEMBL4168217)
Affinity DataIC50: 910nMAssay Description:Inhibition of human recombinant full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50449908(CHEMBL4168217)
Affinity DataKi:  1.09E+4nMAssay Description:Inhibition of MDM2 (unknown origin) preincubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed