BDBM50449568 CHEMBL2448558

SMILES [H][C@]12CCCN(CC[C@@H]1NC(=O)c1cc(Cl)c(N)cc1OC)C2

InChI Key InChIKey=GZSKEXSLDPEFPT-UHFFFAOYSA-N

Data  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50449568   

Target5-hydroxytryptamine receptor 4(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50449568(CHEMBL2448558)
Affinity DataEC50:  98nMAssay Description:Agonism at 5HT4 receptor in rat tunica muscularis mucosaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50449568(CHEMBL2448558)
Affinity DataKd:  3.20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50449568(CHEMBL2448558)
Affinity DataKd:  3.20nMAssay Description:Compound was evaluated for binding to Serotonin 5-hydroxytryptamine 3 receptor in N1E cells using [3H]- -Tropisetron as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article