BDBM50449544 CHEMBL4160544

SMILES CC(C)c1cc2c(Nc3c[nH]nc3C(=O)Nc3ccc(CN4CCN(C)CC4)cc3)nc(C)nc2s1

InChI Key InChIKey=AJLZQJOCQFFRQL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50449544   

TargetCyclin-dependent kinase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50449544(CHEMBL4160544)
Affinity DataIC50: 19nMAssay Description:Inhibition of CDK6 (unknown origin) by Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50449544(CHEMBL4160544)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of human FLT3 by Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50449544(CHEMBL4160544)
Affinity DataIC50: 22nMAssay Description:Inhibition of CDK2 (unknown origin) by Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed