BDBM50449532 CHEMBL4169073

SMILES Cc1ccc(Nc2nc3cc(Oc4ncnc5n(C)ncc45)ccc3n2C)cc1

InChI Key InChIKey=WSDLNWNQRXAJEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449532   

TargetSerine/threonine-protein kinase B-raf(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50449532(CHEMBL4169073)
Affinity DataIC50: 85nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50449532(CHEMBL4169073)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human His-tagged VEGFR2 cytoplasmic domain (789 to 1356 residues) expressed in baculovirus expression system by Z'-Lyte ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed