BDBM50449052 CHEMBL3126692

SMILES CS(=O)(=O)c1ccc(C(=O)Nc2ccc(Cl)c(NC(=O)Nc3ccc(cc3Cl)C(F)(F)F)c2)c(Cl)c1

InChI Key InChIKey=QPWNQEIHZQVOKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50449052   

TargetSmoothened homolog(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50449052(CHEMBL3126692)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at smoothened (unknown origin) expressed in mouse Shh Light2 cells co-expressing Gli-dependent reporter gene assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed