BDBM50448489 CHEMBL3126651

SMILES O=C(Nc1ccc(Nc2ccnc3ccccc23)cc1)c1ccc(Nc2ccnc3ccccc23)cc1

InChI Key InChIKey=MIVZAUUBMZYYER-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50448489   

TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50448489(CHEMBL3126651)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human DNMT3A2/3L using unmethylated DNA as substrate in presence of [methyl-3H]-AdoMetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50448489(CHEMBL3126651)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human N-terminal 600 residues-deleted DNMT1 using hemimethylated (GAC)12 as substrate preincubated for 5 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50448489(CHEMBL3126651)
Affinity DataIC50: 650nMAssay Description:Inhibition of human N-terminal 600 residues-deleted DNMT1 using poly(dI-dC) as substrate in presence of AdoMetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed