BDBM50448486 CHEMBL3126644

SMILES Cc1cc(Nc2ccccc2NC(=O)c2ccc(Nc3ccnc4ccccc34)cc2)nc(N)n1

InChI Key InChIKey=RDZBOUQJVWVNEA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50448486   

TargetHistone-lysine N-methyltransferase EHMT1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50448486(CHEMBL3126644)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of human GLP (734 to 1235) using histone as substrate preincubated for 5 mins followed by substrate addition measured after 5 mins by liqu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50448486(CHEMBL3126644)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of rat recombinant PRMT1 using histone as substrate preincubated for 5 mins followed by substrate addition measured after 6.5 mins by liqu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50448486(CHEMBL3126644)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human N-terminal 600 residues-deleted DNMT1 using poly(dI-dC) as substrate in presence of AdoMetMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed