BDBM504482 2-{5-[(3-Ethoxypyridin-2-yl)oxy]pyridin-3-yl}-N-[(3R,4S)-4-fluoropiperidin-3-yl]pyrimidine-5-carboxamide, bis(trifluoroacetate) salt ::US11065249, Example 3::US11471458, Example 3::US20230405002, Example 3
SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)N[C@@H]1CNCC[C@@H]1F
InChI Key InChIKey=BYEBWRQMQJIYTL-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 504482
Affinity DataIC50: 40nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of DGAT2 in human hepatocytes using [14C]-glycerol as substrate preincubated for 15 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human DGAT2 using 14C decanoyl-CoA as a substrate pre incubated for 2 hrs followed by substrate addition measured after 40 mins by Tril...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of DGAT2 in human hepatocytes using 14C-glycerol as a substrate pre incubated for 45 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair