BDBM50447352 CHEMBL3114469

SMILES O=C(CC1SC(N(CCc2ccccn2)C1=O)c1ccccc1)N1CCC(CC1)N1Cc2ccccc2NC1=O

InChI Key InChIKey=ORUBJGQMGRVXLS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447352   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50447352(CHEMBL3114469)
Affinity DataIC50: 1.37E+3nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP production preincubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50447352(CHEMBL3114469)
Affinity DataKi:  202nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membranes preincubated for 30 mins followed by radioligand addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed