BDBM50447340 CHEMBL3114481

SMILES CC(C)(C)CCN1C(SC(CC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)C1=O)c1ccccc1-c1ccncc1

InChI Key InChIKey=HCROMZSLVLUSFJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447340   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50447340(CHEMBL3114481)
Affinity DataIC50: 99nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP production preincubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50447340(CHEMBL3114481)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membranes preincubated for 30 mins followed by radioligand addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed