BDBM50446848 CHEMBL3115111

SMILES COC1COCCC1N[C@@H]1C[C@H]2CN(C[C@]2(C1)C(=O)N1CCc2ncc(cc2C1)C(F)(F)F)C(=O)OCCN1CCOCC1

InChI Key InChIKey=ABHVKYFWPPHTHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446848   

TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50446848(CHEMBL3115111)
Affinity DataIC50: 97nMAssay Description:Antagonist activity at CCR2 receptor in human THP1 cells assessed as inhibition of MCP-1 induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50446848(CHEMBL3115111)
Affinity DataIC50: 41nMAssay Description:Binding affinity to CCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed