BDBM50446755 CHEMBL3114608

SMILES O=C(N[C@H]1C[C@@H]1c1ccccc1)N1CCC(CC1)Oc1ccc(cc1)-c1nnn[nH]1

InChI Key InChIKey=YPXHRVREWGTCMZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50446755   

TargetCytochrome P450 2C8(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50446755(CHEMBL3114608)
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP2C8 in human liver microsomes after 10 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50446755(CHEMBL3114608)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50446755(CHEMBL3114608)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed