BDBM50446691 CHEMBL3113623

SMILES CC(C)c1noc(n1)N1CCC(CC1)Oc1cc(ncn1)N1CCc2cc(ccc12)S(C)(=O)=O

InChI Key InChIKey=ALAMXYQQAKXSLD-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50446691   

TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50446691(CHEMBL3113623)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at human GPR119 transfected in CHO cells assessed as cAMP accumulation after 2 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50446691(CHEMBL3113623)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element incubated for 2 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50446691(CHEMBL3113623)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at human GPR119 incubated for 2 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed