BDBM50446409 CHEMBL3109724

SMILES Oc1ccc(c(O)c1)-c1cccc2Sc3ccccc3Sc12

InChI Key InChIKey=SFHCRTNQKWZASO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50446409   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50446409(CHEMBL3109724)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 15-LO in human PMNL using arachidonic acid as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50446409(CHEMBL3109724)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50446409(CHEMBL3109724)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of 5-LO in human PMNL using arachidonic acid as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50446409(CHEMBL3109724)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 12-LO in human PMNL using arachidonic acid preincubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed