BDBM50446393 CHEMBL3109644::US9181261, 74

SMILES CC1(C)CN(C(=O)N1Cc1cccc(c1)-c1nccs1)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=BBEFVCQRUUEXMD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446393   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50446393(CHEMBL3109644 | US9181261, 74)
Affinity DataEC50:  1.01E+3nMT: 2°CAssay Description:TrkA kinase activity was measured as the ability of the enzyme to phosphorylate a fluorescently labeled peptide substrate. Buffer salts, reagents, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50446393(CHEMBL3109644 | US9181261, 74)
Affinity DataEC50:  1.01E+3nMAssay Description:Inhibition of TrkA (unknown origin) using fluorescently labeled peptide substrate after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed