BDBM50446352 CHEMBL3109621

SMILES COc1ccc(NC(c2nccs2)c2c(C)[nH]c3ccccc23)cc1OC

InChI Key InChIKey=LLMRMIHLJLRSNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446352   

TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50446352(CHEMBL3109621)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of 1,25(OH)2D3-induced VDR (unknown origin)-mediated CYP24A1 transcription expressed in HEK293T cells after 16 hrs by luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50446352(CHEMBL3109621)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD (unknown origin)-SRC2-3 interaction after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed