BDBM50446351 CHEMBL3109622

SMILES COc1ncccc1NC(c1c(C)[nH]c2cc(C)ccc12)c1cccnc1

InChI Key InChIKey=MWRFNJNGUSICNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446351   

TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50446351(CHEMBL3109622)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of 1,25(OH)2D3-induced VDR (unknown origin)-mediated CYP24A1 transcription expressed in HEK293T cells after 16 hrs by luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50446351(CHEMBL3109622)
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD (unknown origin)-SRC2-3 interaction after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed