BDBM50446348 CHEMBL3109600

SMILES Cc1[nH]c2cc(C)ccc2c1C(Nc1ccc(OC(F)(F)F)cc1)c1ccccc1Cl

InChI Key InChIKey=TZNNEFMPBQBCKN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50446348   

TargetThyroid hormone receptor beta(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50446348(CHEMBL3109600)
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of triiodothyronine-induced thyroid hormone receptor-beta (unknown origin)-mediated transcription expressed in HEK293T cells after 16 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50446348(CHEMBL3109600)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 1,25(OH)2D3-induced VDR (unknown origin)-mediated CYP24A1 transcription expressed in HEK293T cells after 16 hrs by luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50446348(CHEMBL3109600)
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD (unknown origin)-SRC2-3 interaction after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed