BDBM50446192 CHEMBL3109037

SMILES COc1cc(ccc1NC(=O)[C@H]1N[C@H](CC(C)(C)C)[C@@]2([C@@H]1c1cccc(Cl)c1F)C(=O)Nc1cc(Cl)sc21)C(N)=O

InChI Key InChIKey=UOVSZRTTWLJPHE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446192   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Pharma Research

Curated by ChEMBL
LigandPNGBDBM50446192(CHEMBL3109037)
Affinity DataIC50: 177nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with biotinylated p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed