BDBM50445346 CHEMBL3104250

SMILES CC(=NNC(=O)c1cccc(c1)S(=O)(=O)N1CCOCC1)c1cc(Cl)ccc1O

InChI Key InChIKey=NKUDGJUBIVEDTF-UHFFFAOYSA-N

Data  5 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50445346   

TargetLysine-specific histone demethylase 1A(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50: 13nMAssay Description:Inhibition of LSD1 (unknown origin) using dimethyl K4 peptide as substrate assessed as resorufin level by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50: 9.76E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50: 8.04E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50: 13nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataIC50: 13nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  14nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  32nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  35nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  35nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50445346(CHEMBL3104250)
Affinity DataKi:  55nMAssay Description:Non-competitive inhibition of recombinant full-length His6-tagged LSD1 (unknown origin) using dimethylated K4N-terminal H3 peptide as substrate at 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed